Dose-Response-Relationship of COVID – India lost to virus through fear mongering and lockdown
Except a very few pathogens, most of the pathogens known to our scientific world can cause infection only when the initial load or inoculum or dose of the pathogen is ‘sufficient enough’ and otherwise the pathogen may just make a short landfall in vast majority of people and then would disappear to nowhere. Influenza virus certainly follows the rule of dose-response-relationship and why even the Spanish flu pandemic in 1918-1919 had followed the above rule. Human coronavirus 229E (HcoV-229E) has also shown such relationship. In the case of HIV, lower the viral load, longer the incubation period and higher the viral load, shorter the incubation period to make a person from HIV positive to become full blown AIDS has been observed . In the case of Measles, higher the pathogen load, greater the spread and lower the initial dose, poorer the spread of the pathogen has been noticed. In the case of Tuberculosis (TB), sputum positive individuals of bacilli spread the d