Lasting effect post COVID 19 and possible ‘viral immune boosting’

The recent article emerged from United States of America narrating the incidence of several children enduring various health complications post recovery from COVID 19 (viral negativity) has clearly led the medical scientists to postulate the possible role of immune flare up or immune shove of the host may be due to the virus and also the possible involvement of various pathogens and commensal flora in the human body, for the prolonged complications even after the elimination of the virus. 

Such possibility opens up the Pandora’s Box of various possibilities, permutations and combinations of interactions happening between the new virus and the host ecosystem at different levels.  Why after the decline or elimination of the pathogen, the immune mechanism of the host body must still react and complicate itself instead of engaged in healing or repairing work of the host remains strange? 

Does that mean, the immune mechanism of the host, like how it could not recognize the entry virus due to its newness (possibility of re-infection), also fails to realize the elimination of the virus from the host?  Or else the initial trigger created by the novel coronavirus is being utilized by the pathogens in latent form and as well as the commensal flora of the host; may be causing great confusion to the immune mechanism to create wave like reactions, post viral elimination.  The confused immune mechanism is bound to react multi-directionally targeting the host than the pathogen.  

The question is whether the talon of the novel coronavirus or the own defence mechanism is responsible for the deep injury of the host which lasts over several months after the elimination of the virus.   

Another interesting question also we must take up for discussion/debate.  Most of the pathogens known so far would like to have a weak immune defence mechanism of the host to attack.  That may be because the pathogen has evolved over time only to harbour in man but the novel coronavirus may have entered man accidently and hence more than infecting and or harbour within man, may be trying to escape by running around at different organ level and thereby causing confusion to the immunity.   Who knows the virus may be causing such muddle to our immune defence mechanism because when the immunity is so confused, the possibility for the virus to escape is quite high.

If the above possibility has sound scientific ground or footing means, then what should be the possible treatment option – immune boosting herbs and herbal concoctions which lack any iota of science or the immune suppressants?

If the worst affected patients of COVID requires immune suppressants means, should we not review the status of the virus whether it is a real pathogen or harmless new entrant microbe to the human world?  So far we have been going after the virus and declaring all those who have the viral genome as tested by RT-PCR are either vector of the pathogen (when they remain asymptomatic) or COVID 19 patient. 

All the subsequent medical complications thus observed are concluded due to the virus.   The virus alone and or the host mechanism and or the microbes in the host (both pathogens and commensal flora) is responsible for the lasting effect is not yet established. 

Another important question is why such pandemonium does not seem to have occurred in all those who contract the virus in any given population.   Many people show no symptoms despite high viral load and many others even after exposure does not contract virus (remain PCR negative).

SCID mice or wild mice is more susceptible to novel coronavirus or else immune suppressed primate or hyper immune primate is highly susceptible to novel coronavirus at the experimental level may throw some light to our understanding. 

If SCID mice and immune suppressed primates respond poorly to the virus means, we have lot to worry about human ‘immune pandemic’ and not viral pandemic.  Our immunity is the culprit and not the pathogen. 

Earth is for every life form and new species of life would evolve in future as well and which we cannot stop.  We have therefore lots to worry about ‘immune pandemonium and immune paradox’ than the new species of microbes that might evolve in future.

The infectivity / high virulence of the pathogen, or the struggle of the microbe to escape from the host / the struggle of the microbe to understand the host, which situation would really harm the host beg a clear scientific answer. 

The confusion over COVID that we face today may be due to our extra enthusiasm in just mapping the crime and not understanding the criminal but without any understanding or trial, we have concluded the novel coronavirus as the ultimate criminal.  In most cases the crime continues even after the criminal is eliminated. 

The medical science today sustains due to novel coronavirus and hence the medical science may want to continue with the script and narratives only around the novel coronavirus and nothing else.  

Lockdown, economic destruction, quarantine norms, social distancing, use of mask etc., were imposed more to prove the danger of novel coronavirus and COVID 19 than to make a ‘true’ and ‘impartial’ scientific enquiry to know the real quantum of harm the virus can cause. 

The aggression shown by the medical science to make the world believe the virus raises some serious doubts over the role of the virus in the so called COVID 19 deaths.  We need to smell a rat.

Immune defence in ‘paradoxical state’ or in a ‘suppressed state’ would favour a pathogen better? 

From the evolutionary perspective, the ‘paradoxical state’ of immune defence mechanism is likely to favour the pathogen.  No species wants to remain dumb and then survive.  Some level of resistance or uncertainty is essential for every species of life form to remain robust and grow strong. 

When the host immune reaction go mad and act more against the host than against the invader, the invader must use such an opportunity elaborately to enhance its success.  Why the novel coronavirus is not doing so; viral decline happens soon but the health complications last long?

Or else, the virus does not want to harm the host with hyper immune reaction and it wants to limit its role only to elicit the immunity in people with co-morbid vonditions? 

If so means, what is the sense and logic in suggesting the role of immune booting herbs and unproven herbal recipes to prevent the problem?  Proactive use of immune suppressants may be more beneficial is the presumption one can derive from the above scenario. 

On the lighter note, all those who promote obscurantism and occultism in the name of faith medicine and traditional medicine wants to boost the immunity means, should use novel coronavirus and not herbal or metal or mineral recipes. 

After all, novel coronavirus is also ‘natural’ and part of the nature.  Several healing recipes of AYUSH are also formulated with the faecal matter of several animals.  Promote the virus and boost the immunity with the virus should be the catch phrase of those who promote the ancient healing practice instead of attempting to prove the unscientific recipes as ultra-scientific and God given gift.